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Indapamide Action Mechanism
Indapamide is a target-oriented medicine that leaves no stone unturned in obtaining its therapeutic outcome. It initiates its action by stimulating the production of prostaglandin (PGE2), which is known as hypotensive vasodilatory prostaglandin. The other mechanism that this is employs is opposing the activity of two proteins namely KCNE1 and KCNQ1 to carry out its desired effect.
A dosage of 1.25 mg Indapamide is usually recommended to maintain the levels of salt and water within normal limits as well as cure hypertension complication. A morning dose of 2.5 mg of this diuretic medication on a daily basis is recommended to be taken with water for treating edema usually observed in the case of congestive heart failure. Hence, this is found to work as an effective and potent medication to maintain the concentration of salt and water within control.
Indapamide is undoubtedly one of the best and most preferred medications to maintain the levels of water and minerals in normal limits not only in hypertensive individuals but also in those suffering from severe or moderate renal insufficiency.
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