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Roxithromycin Action Mechanism
Roxithromycin eyes the translocation step of the protein transnational elongation process to execute its action on the bacteria. Hence, this medication binds to the 50S ribosomal subunit, which is an essential part of the peptide formation process and thus, results in inhibition of protein synthesis in the bacteria. This activity leads to the impedance of the growth of the bacterial cell and ultimately results in its death.
The general standard dose of Roxithromycin that has been found to exert a potent effect on the different bacterial infections in adults is 150 mg, which should be taken twice a day with regards to either 30 minutes before or 2 hours past your meals. Whereas, children are recommended to take a dose of 2.5 mg to 5.0 mg per kg body weight twice a day, as this has been regarded to be the standard dose in kids.
Roxithromycin does not differentiates gram positive microbes form the gram negative ones and thus, acts in a same potent manner against both the bacteria and is also found to exert a powerful anti-malarial activity.
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